SkinVive vs Rejuran: How to Choose

SkinVive vs Rejuran: How to Choose

Patients researching injectable skin boosters in Seoul often narrow their search to two well-known options: SkinVive and Rejuran. Both are designed to improve skin hydration and texture rather than add volume, but they differ in composition, texture, and how they behave once injected. This page compares SkinVive vs Rejuran using only the treatment details offered at DERNA Clinic, located in Seocho-gu, Seoul, so you can discuss the right option with a doctor during consultation.

What each treatment is

SkinVive is a hyaluronic acid-based skin booster, offered in 1cc, 2cc, and 3cc volumes. It is formulated as a smooth gel that is distributed in small amounts across the treatment area, aiming to improve skin smoothness and hydration from within rather than reshape facial contours.

Rejuran is a different category of booster. It contains polynucleotide, an extract derived from salmon DNA, which is intended to support the skin's natural regeneration processes. At DERNA Clinic, Rejuran is available as the standard Healer formula in 2cc or 4cc, as the denser HB+ formula in 2cc or 4cc for hand injection, and as a separate formulation designed for the delicate eye area.

Who it suits

SkinVive tends to appeal to patients who want a straightforward hydration boost with a relatively simple, single-product approach and flexible dosing by volume. It is often considered by those newer to injectable boosters or looking for a lighter, more diffuse treatment.

Rejuran is frequently chosen by patients interested in supporting skin texture and resilience over a longer course, and by those who want an eye-area option specifically, since not all boosters offer this. Patients who have tried standard hyaluronic acid boosters before and want to try a different mechanism sometimes move toward Rejuran.

Ultimately, in the SkinVive vs Rejuran decision, skin condition, treatment history, and personal goals all matter, which is why a consultation with one of the clinic's doctors is recommended before choosing between them.

Who should avoid it

• Anyone with active skin infections, open wounds, or unresolved inflammation in the treatment area should postpone either treatment until it resolves.
• Patients with known allergies to hyaluronic acid should discuss this with the doctor before considering SkinVive.
• Patients with a history of allergic reaction to polynucleotide-based products, or with certain autoimmune conditions, should raise this during consultation before Rejuran is considered.
• Those who are pregnant or breastfeeding are generally advised to postpone elective injectable treatments; this should be confirmed with the treating doctor.
• Patients on blood thinners or with bleeding disorders should disclose this, as it may affect bruising risk with either product.

This list is general guidance, not a full medical screening. A consultation allows the doctor to review your history and confirm suitability.

How the session goes

Both treatments are administered as in-office injectable procedures and do not typically require general anesthesia. A topical numbing cream may be applied beforehand to reduce discomfort, depending on the doctor's assessment and the treatment area.

For SkinVive, the product is injected in small, evenly spaced amounts across the target area, commonly the cheeks or under-eye region, with the total volume selected from the 1cc, 2cc, or 3cc options based on the treatment plan.

For Rejuran, the Healer formula is typically injected using a fine needle or cannula technique, while the HB+ formula, being denser, is often applied using a hand-injection method that allows for more controlled placement. The eye-specific option follows a similar in-office process adapted for that area. Session length varies by treatment area and volume, but most appointments are completed within a single visit.

Downtime and recovery

Mild redness, small bumps, or temporary swelling at injection points are common with both treatments and usually settle within a day or two. Bruising can occur, particularly with denser formulas like HB+, and may take longer to fade in some individuals. Makeup can often be applied once the skin has settled, though the doctor may advise waiting a short period after the session.

Recovery experience varies from person to person depending on skin sensitivity, the treatment area, and individual healing response. Results are not immediate for either treatment; hydration and texture improvements tend to build gradually over subsequent weeks, and outcomes differ between patients.

Pricing

Prices listed are as provided by the clinic and may not include VAT; the final quote can vary depending on the volume selected, the treatment area, and the outcome of your consultation. Please confirm current pricing and any applicable fees directly with the clinic before booking.

Safety

DERNA Clinic is located at B2F, 17 Seocho-daero 77-gil, Seocho-gu, Seoul, and is open daily from 10:00 to 22:00, with Wednesday mornings from 10:00 to 11:00 reserved for staff training and not available for patient appointments. The clinic's medical team includes doctors with varied academic and clinical backgrounds; for example, Kim Yunseok, CEO, is an orthopedic surgeon and graduate of Inje University College of Medicine, while Ko Bumjun is an otolaryngologist specializing in nose and face contour, formerly chief doctor at AMRED Clinic. As with any injectable procedure, individual results and side-effect profiles vary, and no treatment can be guaranteed to produce a specific outcome. Discussing your medical history, expectations, and any concerns directly with the attending doctor before treatment is the best way to make an informed decision between SkinVive and Rejuran.

Frequently asked questions

Is SkinVive or Rejuran better for under-eye hydration?

Rejuran offers a dedicated eye-area option, while SkinVive is also sometimes used near the under-eye region; the right choice depends on your skin condition and should be discussed with the doctor.

How many sessions are typically needed?

Treatment plans vary by patient and goal, and the doctor will recommend a schedule based on your skin's response after an initial assessment.

Can SkinVive and Rejuran be combined?

Some patients explore combination approaches, but this depends on individual skin condition and should only be planned after a consultation with the clinic's doctor.

Will there be visible bruising after treatment?

Bruising is possible with either treatment, particularly with denser formulas, and tends to fade within days, though healing time varies between individuals.

Do the listed prices include consultation fees?

Pricing may not include VAT or consultation fees, so it is best to confirm the total cost directly with DERNA Clinic before your appointment.